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DC-STAMP激活PI3K/AKT/mTOR信号通路,以调节急性髓性白血病中的PANoptosis

Qian Liang1, Biao Li2, Yue Li3

  • 1Department of Hematology, Zhoukou Central Hospital, Zhoukou Medical Science Research Center, Zhoukou, China.

PloS one
|January 16, 2026
PubMed
概括

在急性髓性白血病 (AML) 中高DC-STAMP表达抑制PANoptosis,促进细胞存活和化学抵抗. 针对PI3K/mTOR途径为这种侵袭性AML亚型提供了潜在的治疗方法.

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