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Updated: Jan 18, 2026

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遗传变异塑造了小鼠脂肪组织中的染色质可访问性景观和转录反应

Juho Mononen1, Mari Taipale2, Marjo Malinen3,4

  • 1Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.

PLoS genetics
|January 16, 2026
PubMed
概括

遗传变异导致染色质可访问性的差异,影响小鼠模型中的基因调节和疾病易感性. 这些发现将遗传差异与关键代谢组织中活跃调节区域的变化联系起来.

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