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Updated: Jan 18, 2026

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells

Published on: March 28, 2025

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PTMA保护线粒体的完整性,以维持 CD8 T 细胞的代谢功能和抗瘤活性

Keling Huang1,2, Xiaoxue Li1,2, Wenhua Liang1,2

  • 1Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children's Hospital, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Science immunology
|January 16, 2026
PubMed
概括

蛋白质氨酸阿尔法 (PTMA) 通过维护线粒体健康来支持抗癌CD8T细胞功能. 这种TCF1-PTMA通路对于持久的免疫反应和改善癌症免疫疗法的有效性至关重要.

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