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日本内血管动脉瘤修复后的开放性手术转换:多中心研究 (JAST-CONVERT研究) 的指示和结果
Koichi Morisaki1, Masaki Sano2, Keisuke Miyake3
1Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Journal of vascular surgery
|January 16, 2026
概括
对于腹腔大动脉动脉瘤 (AAA) 的内血管动脉瘤修复 (EVAR) 后的开放性手术转换 (OSC) 往往是2型内泄症的指示. 在接受OSC的患者中,破裂显著增加了30天的死亡率.
科学领域:
- 血管外科 血管外科
- 血管内修复 血管内修复
- 腹腔大动脉动脉瘤是什么?
背景情况:
- 内血管动脉瘤修复 (EVAR) 是对腹腔大动脉瘤 (AAA) 的常见治疗方法.
- 并发症和长期失效可能需要开放式手术转换 (OSC).
研究的目的:
- 评估AAA的EVAR后的OSC的指示和结果.
- 确定OSC后死亡的风险因素.
主要方法:
- 从13个日本血管中心 (2006-2024) EVAR后接受OSC的208名患者的回顾性分析.
- 收集的数据包括基线特征,OSC的指示,程序细节和结果.
- 主要终点:30天死亡率. 二级终点:整体存活率,动脉瘤相关存活率,不需要再治疗.
主要成果:
- 最常见的表示 (47.1%) 是2型内孔,囊囊扩大.
- 38名患者 (18.3%) 呈现破裂,48名患者 (23.1%) 接受了紧急的OSC.
- 30天死亡率总体为4.3%,但破裂病例为13.2%. 破裂是30天死亡率的重要风险因素 (HR 5.93).
- 10年整体存活率为58.4%,不需要再治疗的比例为87.5%.
结论:
- 在EVAR之后,2型内皮漏洞是OSC的主要征兆.
- 在OSC发生时的动脉瘤破裂显著增加了30天死亡率.
- 需要进一步的研究来优化OSC的选择性指示,并防止治疗延迟.
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