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Updated: Jan 18, 2026

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
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赫索基纳酶从线粒体脱离驱动华堡效应,以支持分隔的ATP生产

Kimberly S Huggler1,2, Kyle M Flickinger1,2, Matthew H Forsberg3

  • 1Morgridge Institute for Research, Madison, WI, USA.

Nature metabolism
|January 16, 2026
PubMed
概括

基酶2 (HK2) 在等离子体状介质中对癌细胞生长至关重要,而不是在标准条件下. 它的作用取决于hexokinase 1 (HK1) 的局部化,影响细胞生长和有氧糖解.

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