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Updated: Jan 18, 2026

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用于疾病建模和治疗的器官:最先进的技术

Mingyi Xu1,2, Dexiao Kong3, Shan Sun4

  • 1Shandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, 50 Shifan Road, Tianqiao District, Jinan, 250031, China.

Experimental hematology & oncology
|January 16, 2026
PubMed
概括

器官技术,使用干细胞创建3D器官模型,通过实现更好的疾病建模和精准医学药物查,彻底改变了再生医学和生物医学研究.

关键词:
疾病建模 疾病建模个性化的治疗方法有机体构造的结构.有机技术有机技术技术制药研究 制药研究

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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