在卡拉奇的糖尿病病患者中评估ACEI和ARB的利用率
Faisal Aslam1, Syed Muhammad Aqeel Abidi2, Syeda Tayyaba Fatima Abidi3
1The Indus Hospital, Indus Health Network, Korangi Crossing, Karachi, Pakistan.
Pakistan journal of pharmaceutical sciences
|January 17, 2026
概括
卡拉奇的糖尿病病患者使用ACE抑制剂 (ACEI) 和ARBs的比例较低,尽管对健康有已证明的好处. 提高医生意识和患者教育对于更好的脏结果至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病 (DM) 是一个全球性的健康问题,糖尿病病是慢性病的主要原因.
- ангиотензин转化酶抑制剂 (ACEI) 和 ангиотензин受体阻断剂 (ARB) 是已建立的治疗方法来减缓糖尿病病的进展.
- 巴基斯坦卡拉奇的ACEI和ARB用于糖尿病病的利用模式尚未研究.
研究的目的:
- 为了确定ACEI和ARB在卡拉奇糖尿病病患者中使用的流行率.
- 确定与ACEI/ARB利用相关的人口和临床因素.
主要方法:
- 卡拉奇阿迦汗大学医院的一项横截面研究 (2021年9月至2022年8月).
- 对118名糖尿病病患者进行了人口统计,ACEI/ARB使用,肌素,缺血性心脏病史和医生类型的分析.
- 统计分析包括千平方测试 (p <0.05显著性).
主要成果:
- 只有26.3%的患者接受了ACEI或ARB;9.3%接受了内分泌学家的护理.
- 女性 (30.9%) 和老年患者 (>65岁,41.9%) 的使用率更高.
- 冠状动脉疾病在66.9%的队列中存在.
结论:
- 在卡拉奇的糖尿病脏病患者中,观察到ACEI和ARB的显著不足使用.
- 临床指南与现实世界处方之间存在差距,这表明需要提高医生意识和患者教育.
- 解决这些差距可以提高的结果,并减少糖尿病病在南亚的负担.
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