关于GUIDE的观点 (指导参与者对癌症试验的理解,包容,多样性和公平):一个临床试验访问干预措施
Kristine A Karvonen1,2,3, Jean A McDougall4, Sarah D Hohl5
1Fred Hutchinson Cancer Center, Seattle, WA, USA. kkarvone@fredhutch.org.
Cancer causes & control : CCC
|January 17, 2026
概括
该计划旨在通过支付患者费用和提供导航来改善癌症临床试验的准入. 患者和提供者反证实了其可行性和可接受性,强调了需要明确的补偿和导航员培训的需要.
科学领域:
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
- 实施科学 实施科学
背景情况:
- 患者和提供者的观点对于开发有效的干预措施来改善癌症临床试验参与至关重要.
- 临床试验访问的现有障碍包括自付费用和缺乏导航支持.
研究的目的:
- 通过检查患者和提供者的观点,开发 GUIDE (向癌症临床试验的理解,包容,多样性和公平性指导参与) 干预措施.
- 优化 GUIDE 的实施,其目的是通过成本补偿和导航来改善对癌症临床试验的访问.
主要方法:
- 与20名瘤病患者和20名提供者进行了半结构化的定性访谈.
- 应用了演性,快速的框架分析,以确定对参与试验和 GUIDE 可接受性,适当性和可行性的影响.
- 实施研究的综合框架和Proctor的实施结果分类法被用来为GUIDE的开发提供信息.
主要成果:
- 患者认为与临床试验相关的费用是参与的重大障碍.
- 提供者一致认为 GUIDE 的干预措施是可以接受的,适当的和可行的.
- 计划的成功取决于明确的报销协议,定义的导航员角色和导航员培训,以建立患者的信任.
结论:
- 与健康相关的社会需求显著影响临床试验参与.
- 该计划显示了解决与健康相关的社会需求和增强试验多样性的潜力.
- 成功实施需要明确的报销基础设施,综合的导航员角色和导航员培训,以满足患者需求并将其与资源联系起来.
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