放射性核素校准器的EURAMET.RI ((II) -S9实验室间比较
Arūnas Gudelis1, Andrei Antohe2, Eszter Bodnár3
1Center for Physical Sciences and Technology, Ionizing Radiation Metrology Laboratory, Savanorių Ave. 231, 02300, Vilnius, Lithuania.
概括
进行了放射性核素校准器的比较,以测量核医学中关键的短寿命放射性核素. 该研究成功地使用重量计方法和对参考值的功率调节平均值方法确定了活动值.
科学领域:
- 计量学 计量学 计量学
- 核医学就是核医学.
- 放射化学 放射化学是指辐射化学.
背景情况:
- 放射性核素校准器对于核医学中准确的活性测量至关重要.
- 短寿命的放射性核素 (例如F-18,Tc-99m,I-131) 需要精确的量化才能有效治疗患者.
- 测量技术的标准化对于实验室间比较至关重要.
研究的目的:
- 组织并进行对短寿命放射性核素的放射性核素校准器进行比较.
- 评估不同放射性核素校准器设置和测量协议的性能.
- 为了确定关键医疗放射性同位素的可靠比较参考值.
主要方法:
- 根据经批准的技术协议,组织了涉及放射性核素校准器的比较.
- 从制造商提供的原始溶液中准备工作溶液,并以各种瓶型分发.
- 活动值通过重力测量来确定,使用HPGe探测器和玛射线光谱仪进行控制测量.
主要成果:
- 活动值是从活动度测量中通过重量计确定的.
- 对比参考值是使用对选定参与者结果的功率调节平均值方法来计算的.
- 为Ga-67,Sm-153和Lu-177.7等放射性核化物准备了特定的溶液和囊大小.
结论:
- 该比较为评估短寿命同位素的放射性核素校准器性能提供了一个框架.
- 用重力测量方法和功率调节平均值方法来确定活动和计算参考值.
- 该研究有助于核医学中放射性测量的计量可追溯性和准确性.
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