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在中年和老年人中同时出现的疼痛模式和抑郁症状:来自全国纵向研究的交叉滞后分析
Peitian Gao1, Guichao Liu1, Zirui Huang1
1School of Health Management, Guangzhou Medical University, Guangzhou, Guangdong, China.
General hospital psychiatry
|January 17, 2026
概括
多部位疼痛和抑郁症显著影响老年人,日常生活活动作为关键环节. 疼痛概况和性别影响了这种关系,突出了综合护理的需要.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 全球老龄化人口面临越来越多的挑战,包括多处疼痛和抑郁症.
- 疼痛和抑郁症之间的双向联系是已知的,但特定的疼痛部位组合和途径需要进一步调查.
研究的目的:
- 调查中年和老年人疼痛部位数量与抑郁症之间的双向关系.
- 探索日常生活工具活动 (IADL) 在这种关系中的调解作用.
- 为了确定与抑郁风险相关的关键疼痛计数和同时发生的模式.
主要方法:
- 查尔斯数据集的三个波 (2015-2020年) 的分析,包括10,077名45岁及以上的成年人.
- 应用交叉滞后调解模型来检查疼痛部位和抑郁症之间的双向关联.
- 利用受限制的立方线和关联规则挖掘来确定关键的疼痛值和组合.
主要成果:
- 证实了疼痛部位数和抑郁症之间的显著双向关系,由IADL调解.
- 抑郁症的风险急剧增加,疼痛部位在稳定之前为0到3个.
- 特定的疼痛组合,包括腰部,脚,膝盖和背部疼痛,构成最高风险.
- 性别差异出现了:女性更容易因IADL损伤而患抑郁症,而男性则经历了多部位疼痛的更直接影响.
结论:
- 多部位疼痛和抑郁症在老年人中表现出双向相互作用,IADL作为一个关键的调解者.
- 疼痛概况和性别显著调节抑郁症的风险.
- 综合和个性化的疼痛管理策略,解决身心健康问题,对于这一群体至关重要.
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