通过抑制铁亡,MUSTN1可以防止肌肉缩:一个ACO1依赖的,外体细胞介导的机制

Zhi Hu1, Hengyong Xu1, Xi Wang1

  • 1State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, PR China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, China; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, PR China.

概括

肌肉骨胚胎核蛋白1 (MUSTN1) 抑制细胞死亡途径铁亡,以促进肌肉再生. 这种由MyoD1调节并通过外体分泌的微蛋白,为肌肉缩提供了潜在的治疗策略.

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