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Yehua Wang¹, Nicole E Smolinski¹, Thuy N Thai²

¹Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, Florida, USA.

Pharmacoepidemiology and drug safety

|January 18, 2026

概括

在4周内延迟婴儿保险入学维持了新生儿研究的样本大小和结果准确性. 这一策略平衡了基于索赔的研究中的案例捕获和数据精度.

科学领域:

医疗保健服务研究医疗服务研究
围产期流行病学围产期流行病学
在医疗保健中的数据分析.

背景情况:

索赔数据对于研究新生儿结局至关重要.
迟到的婴儿保险入学可能导致新生儿结果的错误分类.
母亲索赔可能不准确地捕捉婴儿健康事件.

研究的目的:

在不同的婴儿保险入学场景中评估结果确定准确性.
评估延迟婴儿入学对新生儿结局的影响.
为优化基于索赔的围产期研究策略提供信息.

主要方法:

在美国使用了Merative MarketScan数据库 (2012-2018).
建立了一个与母亲和婴儿相关的队列.
评估结果确定精度与不同的婴儿入学要求.

主要成果:

允许在4周内招生,保留了样本大小,并将类似结果流行率的病例数增加了一倍.
孕产妇索赔对新生儿结果的帮助最小,但对一般结果的特异性降低.
较长的延迟减少了结果的流行率,并增加了母亲的索赔贡献,即使对于新生儿结果.

结论:

结果指导了基于索赔的围产期研究中的结果确定策略.
强调需要针对特定结果的案例确定,以平衡敏感性和特异性.
在4周内延迟婴儿入学是新生儿索赔研究的可行策略.

关键词:

索赔索赔索赔索赔索赔索赔索赔索赔测量过程中的测量.新生儿的结果.

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