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Updated: Jan 20, 2026

Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients
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设计第五代CAR T细胞以克服PD-L1介导的免疫抑制在肺癌中

Yupanun Wutti-In1, Piriya Luangwattananun2, Nunghathai Sawasdee2

  • 1Division of Transfusion science, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand; Cell engineering for Cancer Therapy Research Group, Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|January 18, 2026
PubMed
概括

一种新的CAR T细胞疗法,抗FRα-CAR5,被设计用于阻止PD-L1,显示出对肺癌细胞的增强活性. 这种方法可以改善免疫抑制瘤微环境中的CAR T细胞功能.

关键词:
在CAR T细胞中.化学抗原受体的化学抗原受体FRα FRα 的意思是叶酸受体α的受体是什么免疫检查站封锁免疫检查站封锁非小细胞肺癌是非小细胞肺癌.在PD-L1中.分泌抗PD-L1 scFvv的抗体

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