相关实验视频

Updated: Jan 20, 2026

Zebra II as A Novel System to Record Electrophysiological Signals in Zebrafish
06:15

Zebra II as A Novel System to Record Electrophysiological Signals in Zebrafish

Published on: August 16, 2024

796

肉酸通过斑马鱼的PPARγ信号传递诱导神经发育缺陷

Lixia Peng1, Haoxu Wang2, Yafang Li2

  • 1The Affiliated Hospital of Qingdao University & The Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes) & School of Pharmacy, Qingdao University, Qingdao, China.

Chemico-biological interactions
|January 18, 2026
PubMed
概括

肉中的酸 (CA) 通过影响PPAR-γ.γ等关键基因,导致斑马鱼的神经发育缺陷. 色素和增加PPAR-γ的表达可以减轻这些毒性影响.

关键词:
锡南酸是一种酸.炎症反应是一种炎症反应.网络毒理学网络毒理学这是神经发育缺陷.氧化应激是一种氧化应激.

更多相关视频

Author Spotlight: Manipulating Signaling in Zebrafish Embryos to Decode Cell Fate Decisions07:18

Author Spotlight: Manipulating Signaling in Zebrafish Embryos to Decode Cell Fate Decisions

Published on: October 27, 2023

3.3K
Analysis of Skeletal Muscle Defects in Larval Zebrafish by Birefringence and Touch-evoke Escape Response Assays08:01

Analysis of Skeletal Muscle Defects in Larval Zebrafish by Birefringence and Touch-evoke Escape Response Assays

Published on: December 13, 2013

8.4K

相关概念视频

Zebra II as A Novel System to Record Electrophysiological Signals in Zebrafish06:15

Zebra II as A Novel System to Record Electrophysiological Signals in Zebrafish

The study introduces Zebra II, an advanced system for prolonged ECG acquisition and analysis in zebrafish. This system features an independent perfusion system and multiple-point electrodes for handling multiple fish in controlled environments. Acute effects of Amiodarone were assessed and analyzed with wild-type zebrafish.
796
Optogenetic Signaling Activation in Zebrafish Embryos07:18

Optogenetic Signaling Activation in Zebrafish Embryos

Optogenetic manipulation of signaling pathways can be a powerful strategy to investigate how signaling is decoded in development, regeneration, homeostasis, and disease. This protocol provides practical guidelines for using light-oxygen-voltage sensing domain-based Nodal and bone morphogenic protein (BMP) signaling activators in the early zebrafish...
3.3K
Analysis of Skeletal Muscle Defects in Larval Zebrafish by Birefringence and Touch-evoke Escape Response Assays08:01

Analysis of Skeletal Muscle Defects in Larval Zebrafish by Birefringence and Touch-evoke Escape Response Assays

The zebrafish is now an established and powerful tool for modeling muscular dystrophies, congenital myopathies, and related neuromuscular diseases. Birefringence and touch-evoked escape behavior are two common noninvasive assays used to determine the degree of muscular disorganization and locomotive impairment of zebrafish embryos during early...
8.4K
Light Enhanced Hydrofluoric Acid Passivation: A Sensitive Technique for Detecting Bulk Silicon Defects09:15

Light Enhanced Hydrofluoric Acid Passivation: A Sensitive Technique for Detecting Bulk Silicon Defects

A RT liquid surface passivation technique to investigate the recombination activity of bulk silicon defects is described. For the technique to be successful, three critical steps are required: (i) chemical cleaning and etching of silicon, (ii) immersion of silicon in 15% hydrofluoric acid and (iii) illumination for 1...
9.6K
Using Immunofluorescence to Detect PM2.5-induced DNA Damage in Zebrafish Embryo Hearts05:58

Using Immunofluorescence to Detect PM2.5-induced DNA Damage in Zebrafish Embryo Hearts

This protocol uses an immunofluorescence assay to detect PM2.5-induced DNA damage in the dissected hearts of zebrafish...
4.3K
Inducing Neuroinflammation in Zebrafish Larvae with a Lipopolysaccharide Injection02:28

Inducing Neuroinflammation in Zebrafish Larvae with a Lipopolysaccharide Injection

The video demonstrates the microinjection of lipopolysaccharides (LPS) into the brains of zebrafish larvae to induce neuroinflammation. The larvae are positioned on an agarose-lined dish, the needle is inserted into the brain ventricles, and the LPS is injected. The injected LPS triggers an immune response that leads to...
649