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Updated: Jan 20, 2026

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening
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对一种偏爱NAD的石基酸脱酶突变体的定向进化,以提高催化效率

Xiaobei Liu1, Weiwei Su1, Lingyun Zhang2

  • 1Henan Engineering Research Center of Bioconversion Technology of Functional Microbes, College of Life Science, Henan Normal University, Xinxiang, 453007, China.

International journal of biological macromolecules
|January 18, 2026
PubMed
概括

代谢工程面临着辅助因子失衡,特别是与依赖NADPH的酶,如shikimate dehydrogenase (SDH). 这项研究设计了具有增强NAD利用力的新型SDH突变,克服了以前的效率限制,以改善生物生产.

关键词:
催化效率 催化效率 催化效率配因子偏好 配因子偏好酶工程是一种酶工程.石基酸脱基酶是什么

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