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Updated: Jan 20, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
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长且功能性活跃的RNAs的合成由乙利氨酸化学成分促进

Zidi Lyu1, Adam Katolik1, Iqra Yaseen2

  • 1Department of Chemistry, McGill University, Montreal, Quebec H3A 0B8, Canada.

Nucleic acids research
|January 18, 2026
PubMed
概括

这项研究引入了2'-乙烯基氨酸乙烯基 (2'-ALE) 胺酸,用于合成长,功能性的合成RNA,长度高达215个核酸. 这种新化学物质能够快速合成和降解保护,促进RNA疗法开发.

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