四种不同的益生菌成分和输送形式对清晰对齐器生物膜的抗菌作用:一个随机的单盲交叉试验
Vikas Thakur1, Achint Juneja1, Monis Raza1
1Department of Orthodontics and Dentofacial Orthopaedics, Institute of Dental Studies & Technologies, Ghaziabad, Uttar Pradesh, India.
Journal of the World federation of orthodontists
|January 18, 2026
概括
消费者益生菌,包括饮料和,在短期研究中显著降低了对齐器生物膜和细菌负载. 益生菌饮料对正义牙对齐器表现出最显著的抗菌作用.
科学领域:
- 微生物学 微生物学
- 生物技术是生物技术.
- 牙科科学 牙科科学
背景情况:
- ортодонтический对齐器可以积累细菌负载和生物膜.
- 消费者益生菌配方正在探索抗菌作用.
研究的目的:
- 评估消费者益生菌配方对细菌负载和生物膜对透明牙科对齐器的短期抗菌作用.
主要方法:
- 一项随机四期交叉研究,涉及20名Invisalign使用者.
- 干预措施包括益生菌,冲洗,囊和饮料,按照标签使用.
- 使用共聚焦激光扫描显微镜 (CLSM) 分析细菌计数 (CFU/mL) 和生物膜矩阵 (EPS).
主要成果:
- 与干预前对照组相比,所有益生菌形式都显著降低了总活力计数和EPS光度.
- CFU的减少范围在0.62-1.06 log10之间,益生菌饮料显示最大的下降.
- 在所有干预措施中,CLSM分析显示生物膜矩阵光显著减少.
结论:
- 短期使用各种形式的消费者益生菌显示出对齐器生物膜中显著的抗微生物减少.
- 益生菌饮料表现出最大的抗菌作用.
- 初步发现需要通过特定物种的研究进行进一步的调查,并对临床建议进行更长的后续调查.
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