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中国老年人心血管健康和认知功能之间的性别依赖关系:一个基于社区的队列研究

Bowen Wang¹, Yi Zeng², Virginia Byers Kraus³

¹Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Cerebral circulation - cognition and behavior

|January 19, 2026

概括

通过生命的基本8 (LE8) 来衡量心血管健康,与中国老年女性的更好的认知功能有关,但男性没有. 较高的LE8分数表明女性的认知健康结果有所改善.

科学领域:

老年学是一门学科.
心血管健康心血管健康
认知神经科学认知神经科学

背景情况:

心血管健康对于维持老年人群的认知功能至关重要.
生活必需品8 (LE8) 指数提供了全面衡量心血管健康的指标.
了解心血管健康和认知之间的特定性别关联对于有针对性的干预至关重要.

研究的目的:

研究中国老年人心血管健康 (LE8) 与认知功能之间的性别依赖关系.
检查LE8分数与认知障碍的流行,发病率和下降之间的关系.
探索LE8认知关系中的性别差异.

主要方法:

使用后勤回归分析来评估LE8分数与认知障碍之间的关联.
进行了子组分析,以检查性别差异.
用一个通用线性模型 (GLM) 来比较不同LE8组的迷你心理状态考试 (MMSE) 成绩.

主要成果:

较高的LE8分数与认知障碍的患病率相反相关.
改善的LE8得分与正常基线认知水平的个体发生认知障碍的风险降低有关.
发现发生性认知障碍存在显著的基于性别的关联,较高的LE8得分有利于女性 (OR = 0.29).
较高的LE8得分与整体组和具有正常基线认知能力的人群中较高的MMSE得分有关.

结论:

较高的LE8分数表明,改善心血管健康与中国老年女性更好的认知功能有关.
这种关联在中国老年男性中没有显著的意义.
这些发现强调了心血管健康对认知健康的重要性,特别是在老年妇女中.

关键词:

心血管健康的心血管健康认知功能认知功能生命是必不可少的 8 年龄较大的成年人.

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