一个ESTRO-EPTN德尔菲共识关于质子治疗中的稳定性评估.
Francesco Fracchiolla1, Arturs Meijers2, Ester Orlandi3,4
1UO Fisica Sanitaria, APSS, Trento, Italy.
Physics and imaging in radiation oncology
|January 19, 2026
概括
在质子疗法规划中的稳定性评估缺乏共识. 这项ESTRO研究调查了专家,就关键的不确定性和方法达成一致,指导未来的治疗规划系统开发.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 临床质子疗法临床质子疗法
背景情况:
- 稳定性评估 (RE) 对于质子疗法规划至关重要,但缺乏标准化的国际指南.
- 目前,诊所采用各种自主开发的RE方法,专注于特定的不确定性.
研究的目的:
- 在质子疗法中调查临床RE方法的专家意见.
- 通过建立共识,为未来治疗计划系统 (TPS) 的开发提供信息.
主要方法:
- 德尔菲手术涉及24个欧洲质子疗法中心 (辐射瘤学家和医学物理学家).
- 起草和审查39份关于向强大优化规划过渡的声明.
- 在两轮会议中,根据75%的协议门达成共识.
主要成果:
- 在39个声明中有26个 (66.7%) 达成了共识,其中5个被确定为优先级高.
- 在不确定性 (范围,设置,分数内,解剖学变化) 和RE的方法论上有强烈的共识.
- 关于在规划和剂量报告中使用规划目标量 (PTV) 存在分歧.
结论:
- 埃斯特罗·德尔菲共识为RE的协议领域提供了实际指导.
- 建议制定指导方针,以标准化可再生能源方法和报告.
- 鼓励TPS供应商将软件开发与社区的强有力的规划要求保持一致.
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