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Updated: Jan 20, 2026

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
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改善了互白素-12-分泌化学抗原受体T细胞的抗瘤活性,这些T细胞针对不同癌症的CD176进行向

Melina Umland1, Anna Christina Dragon1,2, Luca Marie Beermann1

  • 1Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie
|January 19, 2026
PubMed
概括

针对CD176 (针对抗原不受限制的细胞因子启动的杀伤重定向的T细胞) 的工程T细胞显示出强大的抗瘤活性. 添加介质素-12增强了它们的有效性,并调节了晚期固体瘤的瘤微环境.

关键词:
CD176 是一个CD176 是一个CD176化学抗原受体 T 细胞互乐金-12是其中一种.固体瘤是一种固体瘤.重定向的T细胞用于抗原不受限制的细胞因子启动的杀死.

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