相关实验视频

Updated: Jan 20, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

当代0.55 T MRI可视化间歇性肺病 - 一项探索性研究

Nadine Bayerl¹, Claudius S Mathy¹, Christina Bergmann^2,3

¹Institute of Radiology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Maximiliansplatz 3, Erlangen 91054, Germany.

European journal of radiology open

|January 19, 2026

概括

低场MRI显示,在没有辐射的情况下评估间歇性肺病 (ILD) 程度的可能性很大. 虽然它准确地测量了整体ILD,但对于特定的特征,如地面玻璃的不透明性和网状化,需要进一步改进.

科学领域:

放射学放射学是一门学科.
肺部医学肺部医学
医疗成像医学成像

背景情况:

间歇性肺病 (ILD) 的诊断和监测通常依赖于高分辨率计算机断层扫描 (HRCT).
HRCT涉及电离辐射,促使人们寻找替代的成像方式.
低场磁共振成像 (MRI) 提供了一种无辐射的方法来可视化肺部结构.

研究的目的:

评估当代0.55特斯拉 (T) MRI用于可视化间歇性肺病 (ILD) 的可行性.
为了比较0.55TMRI的诊断性能与高分辨率计算机断层扫描 (HRCT) 在风湿性ILD患者中.
评估MRI在量化整体疾病程度,地面玻璃不透明度 (GGO) 和网状化方面的能力.

主要方法:

30名患有类风湿性ILD的参与者在31天内接受了HRCT和0.55TMRI.
核磁共振成像协议包括质子密度加权和T2加权的序列.
三名失明放射科医生独立评估了疾病特征,使用半定量评分,通过威尔科克森签名等级和布兰德-阿尔特曼测试分析数据.

主要成果:

在0.55TMRI和HRCT (22.5%与24.5%) 之间,在ILD的总体程度上没有发现统计学上显著的差异.
与HRCT相比,MRI显著高估了地面玻璃不透明度 (GGO) (13.1%对比9.7%) 和低估了网膜 (8.1%对比11.4%).
对于这两种模式,观察者之间有很好的共识 (MRI ICC = 0.94;HRCT ICC = 0.97).

结论:

当代0.55TMRI可用于评估整体ILD程度,与HRCT相比没有显著差异.
尽管在量化GGO和网化方面存在局限性,但0.55TMRI显示出作为总ILD负担评估的无辐射工具的潜力.
在0.55TMRI能够在临床实践中例行实施ILD评估之前,需要进一步的技术进步.

关键词:

计算机断层扫描,X射线诊断成像诊断成像的使用间歇性肺病间歇性肺病磁共振成像技术磁共振成像技术硬化皮质症,全身性硬化皮质症

更多相关视频

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

相关概念视频

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Here, we present practical recommendations for performing thoracic high-resolution computed tomography for diagnosing and assessing systemic sclerosis-related interstitial lung...

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment

Here, we describe the implementation of phase-resolved functional lung MRI as a contrast-agent-free proton MR technique for the assessment of pulmonary ventilation and perfusion dynamics. Validated and applicable across different field strengths and age groups, it could enhance clinical decision-making in the future by aiding in disease quantification and therapy...

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized ¹²⁹Xe MRI to Evaluate Lung Structure-Function

CT and 129Xe MRI provide complementary lung structure-function information that can be exploited for regional analysis using image registration. Here, we provide a protocol that builds from the existing literature for 129Xe MR to CT image registration using open-source...

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Patients with visual deficits after stroke report about different constraints in daily life most likely due to variable compensatory strategies, which are difficult to differentiate in clinical routine. We present a clinical set-up which allows measurement of different compensatory head- and eye-movement-strategies and evaluating their effects on driving...

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-dimensional (3D) phase-resolved functional lung (PREFUL) is a functional magnetic resonance imaging (MRI) technique that allows for quantification of regional ventilation of the whole human lung volume, using tidal breathing and contrast-agent free acquisition for 8 min. Here, we present an MR protocol to collect and analyze 3D PREFUL imaging...

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Lung ultrasound is a noninvasive and valuable tool for bedside evaluation of neonatal lung diseases. However, a relative lack of reference standards, protocols and guidelines may limit its application. Here, we aim to develop a standardized neonatal lung ultrasound diagnostic protocol to be used in clinical...