NAT10通过SQLE介导的胆固醇生物合成驱动肝细胞癌的进展,并且可以通过remodelin进行向

Yumeng Wang1, Xun Yang1, Yihong Dong1

  • 1NHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, The Fourth Hospital of Harbin Medical University, Harbin, China.

iScience
|January 19, 2026
PubMed
概括

在肝细胞癌 (HCC) 中,NAT10被上调,通过调节胆固醇生物合成来促进癌症. 抑制NAT10可以减少瘤的生长,这表明它是HCC的治疗点.

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