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由黄胺诱导的肠道微生物群调节对全球能量代谢的影响:对肥胖的影响

Omar Guzmán-Quevedo^1,2,3, Alana Natalícia Vasconcelos de Araújo^4,5, Pedro A Romero-Juárez^1,2,6

¹Laboratory of Experimental Neuronutrition and Food Engineering, Tecnológico Nacional de México (TECNM)/Instituto Tecnológico Superior de Tacámbaro, Tacámbaro, Michoacán, Mexico.

Frontiers in nutrition

|January 19, 2026

概括

黄素和肠道微生物群 (IM) 影响能量代谢. 本综述探讨了它们的双向相互作用,揭示了肥胖和糖尿病等代谢障碍的潜在策略.

科学领域:

营养科学营养科学
微生物学微生物学
代谢研究研究代谢研究

背景情况:

黄类药物对能量代谢产生有益影响,使其成为肥胖和糖尿病等代谢障碍的潜在治疗剂.
肠道微生物群 (IM) 在代谢调节和宿主健康方面发挥着至关重要的作用,研究表明其通过黄类治疗来调节.
黄类药物和IM在代谢调节中的相互作用是复杂的,需要进一步研究.

研究的目的:

审查黄类药物对肠道微生物群 (IM) 在调节能量平衡中的作用.
讨论IM和黄类药物之间的双向相互作用及其对代谢健康的影响.
阐明这些相互作用背后的机制,以制定营养策略.

主要方法:

文献综述综合了关于黄类-代谢物-宿主相互作用的证据.
对调查黄素对肠道微生物组成和功能的影响的研究分析.
检查IM对黄代谢和宿主能量平衡的影响的研究.

主要成果:

黄胺调节IM的组成和活性,影响主体能量代谢在肝脏,肌肉和脂肪组织等关键组织.
IM可以代谢黄,影响其生物可用性和生物活性.
黄和IM之间的双向通信是代谢调节的组成部分.

结论:

了解黄和IM之间的复杂相互作用对于开发有针对性的营养干预措施至关重要.
黄-IM轴调节为肥胖,2型糖尿病和脂质失调症提供了有前途的治疗途径.
对具体机制的进一步研究可以优化对代谢健康的饮食策略.

关键词:

能量代谢能量代谢黄类化合物黄类化合物这是一种炎症炎症炎症炎症.我们的肠道微生物群.肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖

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