开发下一代NK细胞参与平台,通过整合功率降低的IL-15变体来增强抗瘤活性

Lijun Wang1, Yinhui Ding2, Huifeng Lv1

  • 1Biology, Shanghai EpimAb Biotherapeutics, 702 Zhongke Road, Zhangjiang High-tech Park, Shanghai 201204, China.

Antibody therapeutics
|January 19, 2026
PubMed
概括

下一代自然杀手细胞诱导剂 (NKCEs) 是使用降低功率的IL-15 (IL15v) 开发的,以提高抗瘤功效. 新型IL15v-NKCE在临床前模型中表现出增强的疗效和安全性,提供了有前途的治疗进展.

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