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Updated: Jan 20, 2026

Biotinylated Cell-penetrating Peptides to Study Intracellular Protein-protein Interactions
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Biotinylated Cell-penetrating Peptides to Study Intracellular Protein-protein Interactions

Published on: December 20, 2017

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利用细胞内瘤原蛋白释放细胞毒素

Matthias Schild1, Dennis Gillingham1

  • 1Department of Chemistry, University of Basel 4056 Basel Switzerland dennis.gillingham@unibas.ch.

RSC medicinal chemistry
|January 19, 2026
PubMed
概括

小分子抑制剂被重新用于向的细胞内药物递送. 该策略使用抑制剂-四氨酸合物来激活TCO中的前期药物,使得癌症治疗中细胞毒有效载荷的受控释放成为可能.

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