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Updated: Jan 20, 2026

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用3D打印的多药片用于个性化医疗和精确的口服药物输送在制药实践中:一篇综述

Mahesha Keerikkadu¹, Sathvik Chennamsetty¹, Akshay Shetty¹

¹Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

International journal of pharmaceutics: X

|January 19, 2026

概括

三维 (3D) 打印的多种药丸提供个性化的口服药物输送与受控的药物释放. 然而,生产,监管和稳定的挑战阻碍了它们的广泛临床采用.

科学领域:

制药技术制药技术制药技术
材料科学材料科学材料科学
生物医学工程生物医学工程

背景情况:

三维 (3D) 打印可以创建定制的多药片,将多种药物组合成单一的剂量形式.
这项技术允许通过工程孔隙性和密度来定制药物释放配置文件.
材料和制造技术的进步提高了多种药物的性能.

研究的目的:

审查3D打印多药片技术的现状.
讨论多药片制造,药物选择和释放控制的方法.
突出3D打印多种药丸的潜在影响和翻译挑战.

主要方法:

使用各种3D打印技术,如化沉积建模 (FDM),立体石版 (SLA) 和选择性激光烧结 (SLS).
纳入多种药丸开发的质量设计原则.
探索材料创新,以提高机械强度和稳定性.

主要成果:

通过3D打印的多种药丸可以实现个性化的药物治疗方案和复杂的剂量形式.
设计的多孔性和密度可以控制药物的溶解和释放.
最近的材料创新提高了印刷精度,机械强度和稳定性.

结论:

3D打印的多种药丸对个性化医疗,特别是慢性疾病有很大的前景.
关键的翻译挑战包括生产的一致性,监管批准,可扩展性和长期稳定性.
需要进一步的研究和开发来克服这些临床实施障碍.

关键词:

3D打印的多种药丸增材制造增材制造是一种增材制造.慢性疾病慢性疾病个性化医疗是个性化的医疗.多种药房多种药房

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