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Updated: Jan 20, 2026

Ligand Binding Receptors : G-protein Coupled Receptors
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G-蛋白结合受体激酶2通过脂酶Cγ1限制CCL21诱导的T细胞迁移

Anahi Sanchez1, Caitlin T Winebrenner2, Natalia Garcia1

  • 1Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.

Receptors (Basel, Switzerland)
|January 19, 2026
PubMed
概括

像GRK2这样的G蛋白结合受体激酶 (GRKs) 调节C-C化学受体7 (CCR7) 信号偏差. 根据配体,GRK2促进了明显的CCR7内化和G蛋白招募,从而影响T细胞的反应.

关键词:
与G蛋白结合的受体激酶受体.一个T细胞细胞.这是一种化学物质,chemokine.带带偏差的信号传输.

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