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Updated: Jan 20, 2026

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在人类中,微塑料暴露引起的肠道微生物组重塑

Xin-Yue Yang¹, Zhong-Wei Zhang¹, Guang-Deng Chen¹

¹International Science and Technology Cooperation Base for Efficient Utilization of Nutrient Resources and Fertilizer Innovation, College of Resources, Sichuan Agricultural University, Chengdu, People's Republic of China.

|January 19, 2026

概括

微塑料 (MPs) 改变人类肠道微生物群,减少有益的细菌和短链脂肪酸. 这种失生症可能与IBD和癌症等疾病有关,尽管研究仍在进行中.

科学领域:

环境健康环境健康
微生物学微生物学
人类健康人类健康人类健康

背景情况:

微塑料 (MP) 对动物肠道微生物群的影响已知,但人类数据很少.
人类肠道微生物群的差异需要对MP影响进行具体的研究.
MP诱导的肠道失调和人类疾病病原体之间的潜在联系正在出现.

研究的目的:

审查目前关于微塑料对人类肠道微生物群的影响的证据.
分析微塑料诱导的失生症和人类疾病之间的潜在联系.
探索人类微塑料暴露研究的机制和局限性.

主要方法:

对人类微塑料暴露的横截面研究 (例如,一次性餐具中的热食品).
分析微塑料暴露与肠道微生物组的组成和功能之间的关联.
对微塑料对人类肠道细菌影响的现有文献的审查.

主要成果:

微塑料暴露改变了细菌的丰度,增加了一些 (例如,Enterobacteriaceae) 和减少其他 (例如,Bacillota).
观察到的变化与减少的酸盐和短链脂肪酸水平相关.
对于某些细菌 (例如,Lachnospiraceae) 存在矛盾的发现,这些细菌可能与肥胖和IBD等疾病有关.

结论:

微塑料会诱导人类的肠道失调,影响微生物的多样性和功能.
微塑料诱导的失生症是人类疾病发病的潜在因素.
需要进一步的研究来澄清机制,并解决人类暴露评估的局限性.

关键词:

微塑料是一种微塑料.我们的肠道微生物群.人类疾病人类疾病病原生物是一种生物.益生菌是一种益生菌.

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