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Updated: Jan 20, 2026

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

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数字双驱动,以人为中心的人体工程学风险预测在汽车和工业组装:一个集体案例研究

Touria Benazzouz1, Aissa Ouhadou Iman1, Mihoubi Saloua1

  • 1Laboratory of Research in Intelligent and Sustainable Technologies (LaRTID), National School of Applied Science, Cadi Ayyad University (UCA), Marrakech, Morocco.

Ergonomics
|January 19, 2026
PubMed
概括

数字双胞胎 (DTs) 将汽车组装的工程学从反应性预防转变为适应性,个性化解决方案. 这一进步有助于减少肌肉骨风险,并支持为工业5.0做好准备的灵活,更安全的制造业.

关键词:
数字双胞胎 数字双胞胎 数字双胞胎工业5.0 工业 5.0 工业 5.0 工业 5.0 工业集成制造制造集成制造制造人体工程学风险预测预测以人为中心的设计

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Herein we describe a novel method to generate antigen-specific T cell receptors (TCRs) by pairing the TCRα or TCRβ of an existing TCR, possessing the antigen-specificity of interest, with complementary hemichain of the peripheral T cell receptor repertoire. The de novo generated TCRs retain antigen-specificity with varying...
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