在患有肠-大脑相互作用障碍的儿童中,结构性胃肠道疾病的重叠
Andrew Krueger1, Umber Waheed2, Neha Santucci3
1Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Neurogastroenterology and motility
|January 19, 2026
概括
儿科患者经常有重叠的肠-大脑相互作用障碍 (DGBI) 和结构性胃肠道疾病. 认识到这种重叠对于有效管理和改善生活质量至关重要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 肠-大脑相互作用
- 功能性胃肠道疾病 功能性胃肠道疾病
背景情况:
- 肠-大脑相互作用障碍 (DGBI) 在儿童和成人中很常见,影响生活质量.
- 存在无明确结构原因的胃肠道症状的DGBI,涉及生物心理社会因素.
- 研究正在探索DGBI病理生理学中的肠-大脑轴,内脏过敏和超警.
研究的目的:
- 本综述为临床医生提供了关于DGBI与炎症性肠病,腹腔疾病和性肠道疾病重叠的儿科研究的最新概述.
- 突出了儿童患者中常见的DGBI亚型,这些患者有结构性胃肠道疾病,包括功能性腹痛,易怒肠综合征和功能性便秘.
- 强调认识到DGBI重叠的重要性,当症状在结构性疾病的治疗中仍然存在时.
主要方法:
- 儿科研究的总结性综述.
- 专注于临床表现,诊断和管理.
- 评估症状重叠和诊断挑战.
主要成果:
- 功能性腹痛,刺激性肠综合征和功能性便秘是患有结构性胃肠道疾病的儿科患者常见的DGBI.
- 在DGBI和结构性胃肠道疾病之间存在显著的症状重叠和诊断挑战.
- 症状的持续,尽管结构状况的管理,保证考虑共患的DGBI.
结论:
- 临床医生必须意识到儿科患者具有结构性胃肠道疾病的并发性DGBI的可能性.
- 在怀疑DGBI时,可能需要一个多学科的方法来提供全面的护理.
- 解决并发性DGBI可以改善患者的生活质量,提供者满意度和临床结果.
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