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Updated: Jan 21, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
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Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

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ASTWAS:在核心驱动的TWAS中建模替代多基和SNP效应,揭示了复杂特征的新型遗传关联

Yan Wang1, Lei Wang1,2, Nan Sheng1

  • 1Key laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education, College of Computer Science and Technology, Jilin University, No. 2699 Qianjin Street, Chaoyang District, 130012 Changchun, Jilin, China.

Briefings in bioinformatics
|January 19, 2026
PubMed
概括

替代多氨基基化 (APA) 影响基因表达,但在遗传关联研究中尚未研究. 我们的新工具,ASTWAS,提高了检测APA使用的遗传影响的功率,特别是复杂的相互作用.

关键词:
替代多基化 (APA) 是一种方法.复杂的特征易感性 复杂的特征易感性核心方法 核心方法非线性遗传效应是一种非线性遗传效应.转录组范围的关联研究 (TWAS)

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