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Updated: Jan 21, 2026

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在现实世界条件下,由双室无心脏起器维护的心房心房同步
Pascal Defaye1, Vivek Y Reddy2, James E Ip3
1CHRU Grenoble Alpes, Grenoble, France.
概括
双室无心脏起器在日常活动中实现了超过96%的心房同步. 这表明了系统的系统性.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
背景情况:
- 双室无线心脏起器 (LP) 系统利用无线植入物到植入物 (i2iTM) 通信来协调心房和心室设备.
- 在日常生活中评估心房 (AV) 同步对于在现实条件下评估心脏起器性能至关重要.
研究的目的:
- 在24小时的门诊期间,评估双室无心脏起器 (LP) 系统的心房 (AV) 同步.
- 评估双腔LP在患者的安全性和性能,标准节奏指示.
主要方法:
- 一项前性单臂多中心临床研究 (NCT05252702) 招募了需要双室节奏调节的患者.
- 患者在恢复日常活动的同时,通过霍尔特设备进行了24小时的门诊监测.
- 独立的核心实验室分析根据节奏和传感AV延迟参数判断了同步节拍的比例.
主要成果:
- 在96.7%的节拍中实现了平均AV同步,超过了A-to-V (93.4%) 和V-to-A (92.1%) 的传输成功率.
- 在门诊环境中,AV同步在各种心率和节奏/传感配置中始终保持在90%以上.
- 在患有鼻节功能障碍和AV阻塞的患者之间没有观察到AV同步的显著差异.
结论:
- 双室无节奏系统在24小时的日常生活中表现出高的整体AV同步 (>96%).
- 这证实了在现实 ambulatory 条件下保持真正的双室 DDD (R) 节奏的能力.
- 该系统对需要高级节奏支持的患者表现有希望.
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