急性疾病后11至18个月的长期mpox后果:美国两座城市的队列研究
Preetam A Cholli1, Jason Zucker2, Karen J Vigil3
1Centers for Disease Control and Prevention, Atlanta, Georgia (P.A.C., F.S.M., P.J.W., M.M.T., D.L.H., A.A., A.K.R., S.M.O.).
Annals of internal medicine
|January 19, 2026
概括
感染后11-18个月持续的mopox后续症状很常见,影响外观和功能. 精神行为症状在mpox幸存者和处于危险阶段的个人中是相似的.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 在2022年全球疫情爆发之前,对持久性mopox后果的知识有限.
- 2022年的mopox疫情涉及Clade II病毒菌株.
研究的目的:
- 在mopox诊断后11-18个月的持续后续症状的特征.
- 为了比较受MPOX影响和处于危险状态的个体之间的心理和行为影响.
主要方法:
- 一项队列研究在纽约市和休斯顿进行.
- 招募了参加性病,艾滋病毒或PrEP诊所的成年人.
- 参与者完成了心理社会评估;临床医生评估了身体后果.
主要成果:
- 58%的mpox后参与者出现了持续的后果,主要与外表有关 (56%).
- 13%的人经历了功能性后续,包括直肠 (50%) 和尿道 (35%) 功能障碍.
- 精神行为症状在mopox幸存者和对照者之间是相似的.
结论:
- 感染后11-18个月持续的mopox后续经常发生.
- 后果往往涉及外表变化和功能缺陷,具有社会和性影响.
- 需要进一步的研究来了解mopox的长期影响.
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