巴西性工作者口服人类乳头瘤病毒的流行率
Emma Smoler1, Gustavo Eidt2, Álisson Bigolin3
1Epidemiology and Health Promotion, New York University College of Dentistry, USA.
概括
高风险口服人类乳头瘤病毒 (HPV) 在巴西7.2%的性工作者中被发现. 在某些地区和那些每周有很多性伴侣的地区,患病率更高,这表明需要有针对性的干预措施.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 病毒学 病毒学
背景情况:
- 性工作者是性传播感染风险较高的人群,包括人类乳头瘤病毒 (HPV).
- 口腔HPV感染与口腔癌有关,了解其在高风险群体中的患病率对于公共卫生战略至关重要.
研究的目的:
- 在巴西各地的男性和女性性工作者中确定致癌性口腔HPV感染的流行率.
- 在这个人群中确定与口腔HPV感染相关的社会行为因素.
主要方法:
- 一项横截面的多中心研究利用受访者驱动的抽样 (RDS) 来招募来自巴西所有地区的940名性工作者 (2019-2023年).
- 结构化采访收集了社会人口统计和性行为数据;口腔样本通过PCR分析了HPV基因型.
- 使用RDS-II估计和强大的Poisson回归来分析流行率.
主要成果:
- 高风险口服HPV的患病率为7.2% (95%CI为4.1-10.3).
- 来自中西部/东南/南部地区的性工作者 (aPR 4.39) 和报告超过每周15个性伴侣的性工作者 (aPR 4.11) 观察到更高的调整后流行率.
- 大多数参与者是女性 (84.2%),在性工作中工作了不到5年 (54.2%),并报告了一致的避孕套使用 (53.4%).
结论:
- 在巴西的性工作者中,口腔HPV患病率存在显著差异,受结构和行为因素的影响.
- 调查结果强调了针对这一高风险群体进行量身定制的公共卫生干预措施的必要性,包括HPV疫苗接种和全面的性健康教育.
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