Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Phylogeny01:23

Phylogeny

56.9K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
56.9K
Lineage Commitment01:21

Lineage Commitment

4.1K
Commitment is the  process whereby stem cells:
4.1K
How Data are Classified: Numerical Data00:59

How Data are Classified: Numerical Data

36.8K
Data that are countable or measurable in specific units are called numerical or quantitative data. Quantitative data are always numbers. Quantitative data are the result of counting or measuring the attributes of a population. Amount of money, pulse rate, weight, number of people living in a town, and number of students who opt for statistics are examples of quantitative data.
Quantitative data may be either discrete or continuous. All quantitative data that take on only specific numerical...
36.8K
How Data are Classified: Categorical Data01:11

How Data are Classified: Categorical Data

42.9K
A variable, usually notated by capital letters such as X and Y, is a characteristic or measurement that can be determined for each member of a population. Data are the actual values of variables. They may be numbers, or they may be words. Datum is a single value.
Data are classified based on whether they are measurable or not. Categorical data cannot be measured; instead, it can be divided into categories. For example, if Y denotes a person's party affiliation, some examples of Y include...
42.9K
Persuasion Strategies01:52

Persuasion Strategies

43.0K
Researchers have tested many persuasion strategies, including the foot-in-the door and the door-in-the-face techniques, in a variety of contexts. Ultimately, the principles are effective in selling products and changing people’s attitude, ideas, and behaviors (Cialdini & Goldstein, 2004).
43.0K
Data Reporting and Recording01:24

Data Reporting and Recording

5.3K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Improving Inference from Reported Concentrations in Environmental Surveillance by Modeling the Statistical Features of Digital PCR.

ACS ES&T water·2026
Same author

Real-time estimation of pathogen transmission dynamics from wastewater.

Nature communications·2026
Same author

Wastewater-based sequencing of respiratory syncytial virus to investigate lineage dynamics and antigenic site mutations: a retrospective genomic epidemiology study.

The Lancet. Microbe·2026
Same author

SciPhy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data.

Nature communications·2026
Same author

Assessing the inference of single-cell phylogenies and population dynamics from CRISPR lineage recordings.

PLoS computational biology·2026
Same author

From clinics to sewers: leveraging environmental surveillance and whole genome sequencing to inform transmission of ESBL-<i>Escherichia coli</i> in Switzerland.

Applied and environmental microbiology·2026

相关实验视频

Updated: Jan 21, 2026

Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain
09:44

Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain

Published on: May 20, 2022

3.6K

从顺序系谱追踪数据中解决细胞系谱的策略.

Nicola Mulberry1, Tanja Stadler2

  • 1Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.

Theoretical population biology
|January 19, 2026
PubMed
概括

新的基于CRISPR的谱系记录器通过遗传突变捕捉细胞历史. 这项研究确定了使用这些动态记录系统准确重建细胞家族树的条件.

科学领域:

  • 分子生物学分子生物学
  • 遗传学 遗传学 是一个
  • 生物信息学是一种生物信息学.

背景情况:

  • 分子记录设备和测序的进步使得数千个细胞的血统追踪成为可能.
  • 动态谱系记录器利用基于CRISPR的系统的遗传突变进行持续的遗传记录.
  • 现在可以获得序列突变,提供比传统方法更丰富的基因信息.

研究的目的:

  • 为了建模顺序编辑的记录系统.
  • 分析实验条件,以准确地进行遗传学重建.
  • 了解动态谱系记录器的信息内容.

主要方法:

  • 一个顺序编辑的记录系统的建模.
  • 突变积累和家族遗传重建的理论分析和模拟.
  • 确定参数模式,以准确追踪血统.

主要成果:

  • 已确定了明确的参数模式,其中基于距离的方法可以准确地解决细胞系谱.
  • 该研究发现了条件,使得高概率的精确的遗传学重建.
  • 理论结果可以指导对谱系追踪研究的实验设计.

结论:

关键词:
谱系追踪 谱系追踪 谱系追踪 谱系追踪遗传学信息内容 遗传信息内容遗传学重建的研究.理论上的界限.

更多相关视频

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice
07:48

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice

Published on: December 18, 2015

18.1K
Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
09:06

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

8.8K

相关实验视频

Last Updated: Jan 21, 2026

Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain
09:44

Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain

Published on: May 20, 2022

3.6K
A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice
07:48

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice

Published on: December 18, 2015

18.1K
Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
09:06

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

8.8K
  • 简单,高效的重建方法可以在特定条件下准确地解决细胞的细胞系.
  • 了解记录器信息内容对于推进血统追踪至关重要.
  • 这项工作为优化基于CRISPR的谱系追踪实验设计提供了一个框架.