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Updated: Jan 21, 2026

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
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用于化压力介导癌症治疗的ROS响应的自燃性聚合物前药物

Anup Dey1, Jeongjin Lee1, Minsung Park2

  • 1School of Chemical Engineering, College of Engineering, Sungkyunkwan University (SKKU), Seobu-ro 2066, Jangan-gu, Suwon 16419, Republic of Korea.

Journal of controlled release : official journal of the Controlled Release Society
|January 19, 2026
PubMed
概括

这项研究引入了一种新型聚合物前药物,该前药物释放氧化 (NO) 并在瘤中清除谷氨. 这种有针对性的方法显示出强大的抗癌作用和最小的毒性,提供了一种新的氧化还原反应疗法.

关键词:
谷氨缺乏症 谷氨缺乏症氧化氧化是什么?聚合物前药物 聚合物前药物有反应性氧物种的反应性氧物种.自焚聚合物是一种自焚性聚合物.癌症治疗 治疗 治疗 癌症

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