饮食,炎症性皮肤疾病和心理健康:对当前证据的全面审查
Bochen Li1, Ruotong Zhang1, Rachel Gibson1
1Department of Nutritional Sciences, School of Life Course and Population Sciences, King's College London, London, United Kingdom.
Clinical nutrition ESPEN
|January 19, 2026
概括
饮食因素影响慢性炎症性皮肤疾病 (CISD) 和心理健康. 促进健康的饮食与减少CISD和心理健康状况的严重程度有关,这强调了综合研究的必要性.
科学领域:
- 皮肤病学和精神病学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 长期炎症性皮肤疾病 (CISDs),如,牛皮和亚托邦性皮肤炎,与严重的心理痛苦和社会耻辱有关.
- 饮食是一种可修改的因素,因其对CISD和心理健康的潜在影响而越来越受认可.
- 本综述综合了当前关于饮食,CISD和心理健康之间的复杂相互关系的证据.
研究的目的:
- 系统地调查和评估有关饮食因素,CISD和心理健康状况之间的相互联系的现有证据.
- 为了确定常见的饮食暴露,CISD和精神健康结果进行了研究.
- 突出文献上的差距,并提出未来的研究方向.
主要方法:
- 在六个主要数据库 (MEDLINE,CINAHL,Embase,Scopus,Cochrane CENTRAL,PROSPERO) 进行了全面的系统文献搜索,截至2024年4月.
- 在根据预先定义的资格标准选了1,739个独特记录后,包括了22项研究.
- 数据被提取和合成,重点是研究设计,人口,饮食因素,CISD和心理健康结果.
主要成果:
- 是最受研究的CISD,食物消耗/频率是最常见的饮食暴露,抑郁是最常见的心理健康结果.
- 有益的饮食模式,成分和行为 (营养丰富,促进健康) 始终与CISD和心理健康状况的风险/严重性降低有关.
- 观察到CISD和心理健康结果之间存在强烈的正相关性. 证据的强度有限,只有很少的队列研究和RCT. 很少有研究同时研究这三个领域.
结论:
- 饮食是饮食,CISD和心理健康的相互连接系统中的可修改,潜在的成本效益因素.
- 目前的证据支持所有三个领域的协会,需要综合研究和干预.
- 未来的研究应该利用大规模的综合数据来澄清这些复杂的相互关系,可能使用饮食 → CISDs (调解者) →心理健康途径.
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