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Updated: Jan 21, 2026

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在人类乳腺癌细胞系中,IFNγ诱导的PD-L1表达的Src-依赖调节

Chihiro Hayashi1, Yuto Mizuno2, Yu Iida3

  • 1Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa, 236-0004, Japan.

Journal of pharmacological sciences
|January 19, 2026
PubMed
概括

Src氨酸激酶调节三阴性乳腺癌 (TNBC) 中的PD-L1表达. 抑制Src可以增强T细胞对TNBC的活性,这表明一种潜在的新疗法可以改善对这种侵袭性癌症的免疫反应.

关键词:
分化集群8阳性T细胞 (CD8(+) T细胞)干扰素玛 (IFNγ) 是一种干扰素.编程死亡链条1 (PD-L1) 编程死亡链条1Src 铁氨基激酶 (Src) 的作用三重阴性乳腺癌 (TNBC) 是一种

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