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Updated: Jan 21, 2026

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
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位点和功能屏幕识别了与增加乳腺癌风险相关的PALB2误解变异

Rick A C M Boonen1, Sabine C Knaup1, Roberta Menafra2

  • 1Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

Nature communications
|January 19, 2026
PubMed
概括

对PALB2误解变异的功能查显示,有害突变增加了乳腺癌风险. 这项研究有助于分类具有不确定的意义的变异 (VUS) 和管理患者护理.

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