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Updated: Jan 21, 2026

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
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使用单细胞hdWGCNA识别和实验验证重点线粒体相关基因在死性肠球炎中

Yuehua Chen1,2, Kexin Gao2, Ning Chen2

  • 1Department of Pediatric Surgery, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.

Pediatric research
|January 19, 2026
PubMed
概括

结核性肠球炎 (NEC) 涉及显著的单细胞透. 这项研究确定了Acyl-CoA合成酶长链家族成员1 (ACSL1) 作为一个关键的线粒体基因,驱动NEC病原和免疫失调.

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