在EXCOR支持的儿童中等候名单死亡率:对日本Excor注册表的分析
Takaya Hoashi1, Mariko Asase2,3, Heima Sakaguchi4
1Department of Pediatric Cardiac Surgery, Saitama Medical University International Medical Center, Hidaka, Japan.
概括
在日本,使用EXCOR儿科进行心室辅助器件 (VAD) 治疗,显示了桥梁到移植的良好结果. 植入时体重低是死亡的风险因素,但整体存活率很高.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管外科心血管外科
- 医疗器械 医疗器械
背景情况:
- 对于等待移植的儿科心力衰竭患者来说,心室辅助器件 (VAD) 是至关重要的.
- 儿科EXCOR系统是儿童广泛使用的VAD.
- 了解日本等特定地区的结果对于全球VAD治疗很重要.
研究的目的:
- 为了评估日本EXCOR儿科VAD治疗的预后结果.
- 确定影响儿科VAD患者等候名单死亡率的风险因素.
主要方法:
- 对137名接受EXCOR儿科VAD作为桥梁到移植的儿科患者的回顾性分析.
- 从2012年8月到2025年3月收集的数据.
- 评估风险因素,包括诊断,年龄,体重和支持类型.
主要成果:
- 平均年龄为15.4个月,平均体重为7.2公斤.
- 扩张性心肌病是最常见的诊断 (72.9%).
- 一年生存率为92.9%,超过一年的支持率为51.0%. 体重<5kg是唯一的死亡风险因素 (HR 2.43).
结论:
- 在日本,EXCOR儿科VAD治疗显示了桥梁到移植的良好预后结果.
- 植入时的低体重是死亡的重要风险因素.
- 在不同初级心脏诊断中,结果是可比的.
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