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测量骨肌肉质量的参考方法:一个关键的视角

Steven B Heymsfield¹, Houchun H Hu², Edvin Johanssen³

¹Pennington Biomedical Research Center, LSU System, Baton Rouge, Louisiana, USA.

Journal of cachexia, sarcopenia and muscle

|January 20, 2026

概括

没有一个单一的黄金标准来测量人类骨肌肉 (SM) 质量. 本次审查强调了需要标准化的协议和精确的术语在体内方法,以准确的SM量化.

科学领域:

生理学生理学生理学
生物医学工程生物医学工程
医疗成像医学成像

背景情况:

骨肌肉 (SM) 在健康和疾病中起着至关重要的作用.
量化人类的SM质量缺乏普遍接受的黄金标准方法.
目前的方法被广泛分为体外和体内方法.

研究的目的:

批判性地审查现有的 in vivo 方法来量化人类骨肌肉质量和组成.
确定当前参考方法的局限性及其对衍生技术的影响.
提出建议,以提高SM测量的准确性,可复制性和清晰度.

主要方法:

对骨肌肉量化的体外和体外方法的系统审查.
在体内方法的分类:参考 (上层) 和二次 (下层) 方法.
对参考方法 (CT,MRI,DXA) 的协议,术语和验证程序进行批判性分析.

主要成果:

实验室内方法很少报告,不适合当前的临床使用.
三种体内方法 (CT,MRI,DXA) 被认为是参考标准,但缺乏标准化的协议和术语.
下层方法需要与参考方法进行校准,传播任何不准确性.
在采集协议和对参考方法的图像分析中存在显著的变化.

结论:

对于体内骨肌肉质量量量化,目前还没有确定的黄金标准.
标准化的协议和精确的术语对于CT,MRI和DXA在SM测量中至关重要.
未来需要专家的共识,以建立最佳指导方针来分析肌肉质量和组成.

关键词:

身体构成身体组成卡赫西亚 (Cachexia) 是一种缓解症.脆弱脆弱脆弱脆弱脆弱营养不良营养不良营养不良营养评估营养评估肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖这种类型的麻症是sarcopenia.

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