吸烟状态对骨折愈合时间的影响:回顾性队列分析
Hamza Ahmed1, Aarish Azeem1, Asher Ishaq2
1Trauma and Orthopaedics, Salford Royal NHS Foundation Trust, Salford, GBR.
Cureus
|January 20, 2026
概括
与以前的吸烟者和从未吸烟者相比,目前的吸烟者经历明显延迟的骨折愈合. 戒烟对于优化骨折恢复时间表至关重要.
科学领域:
- 整形外科 整形外科 整形外科
- 创伤外科 手术 创伤外科
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 吸烟是已知的骨代谢受损的风险因素.
- 当前,以前和从未吸烟对骨折愈合结果的不同影响需要进一步阐明.
研究的目的:
- 为了研究吸烟状态和成年长骨骨折中放射性结合时间之间的关联.
- 量化各类吸烟者的骨折愈合时间差异.
主要方法:
- 在英国一家主要创伤中心对成年长骨折进行了回顾性队列研究.
- 吸烟状态分为当前,前 (禁烟≥1年) 或从未吸烟者.
- 使用桥梁皮层和骨 (RUST) 骨折的放射性联合评分来评估放射性联合;统计分析包括ANOVA和多变量考克斯回归.
主要成果:
- 在吸烟群体中观察到愈合时间的显著差异 (p < 0.001).
- 与以前 (17.2 ± 4.0 周) 和从未吸烟的人 (15.3 ± 3.0 周) 相比,目前吸烟者表现出明显缓慢的愈合 (20.1 ± 5.0 周).
- 卡普兰-梅尔曲线和调整后的考克斯回归证实了当前吸烟者的延迟结合.
结论:
- 在吸烟状态和延迟骨折愈合之间存在明确的剂量反应关系.
- 当前吸烟者面临的愈合时间最长,而前吸烟者显示部分恢复,从未吸烟者愈合最快.
- 建议将戒烟咨询与骨折管理相结合,以改善患者的治疗结果.
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