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Updated: Jan 21, 2026

RNA Secondary Structure Prediction Using High-throughput SHAPE
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使用高度特定的结构碎片预测潜在的不良药物反应

P I Savosina1, D A Filimonov1, D S Druzhilovskiy1

  • 1Institute of Biomedical Chemistry, Moscow, Russia.

Biomeditsinskaia khimiia
|January 20, 2026
PubMed
概括

在 silico 方法通过识别有害的化学结构来预测药物毒性. 这项研究发现,五种临床试验药物可能会由于潜在的表皮生长因子受体或二基酶4的抑制而带来风险.

关键词:
药物不良反应 药物不良反应在学研究中.结构碎片 结构碎片不良分子目标是不必要的分子目标.

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