氨酸甲基化对抗TEAD3-介导的抑制,通过破坏RUNX2-Sequestrating凝聚物来促进骨质分化

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Updated: Jan 22, 2026

In vitro Methylation Assay to Study Protein Arginine Methylation
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In vitro Methylation Assay to Study Protein Arginine Methylation

Published on: October 5, 2014

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Lei Cao1,2, Ruohui Han1,3, Hui Xiong4

  • 1State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Key Laboratory of Medical Epigenetics, Department of Endodontics, Tianjin Medical University School and Hospital of Stomatology & Tianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, Tianjin Medical University, Tianjin, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 20, 2026
PubMed
概括

蛋白质氨酸甲基转移酶调节骨的修复. 转录因子TEAD3的氨酸甲基化控制了干细胞中的骨质生成,为骨再生提供了新的治疗点.

关键词:
我们的 TEAD TEAD 团队.氨酸甲基化的阿尔金因.骨再生 骨再生表观遗传学是指表观遗传学.骨质性分化的骨质性差异化牙周带干细胞 牙周带干细胞

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