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Updated: Jan 22, 2026

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
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卡尔帕因-MMP3的激活限制了蛋白质转导域TAT介导的蛋白质递送过程中的核吸收

Jin Hyeop Kim1,2, Eun Young Choi3, Yeon-Jun Lee1,2

  • 1Department of Biotechnology, CHA University, Pocheon, Republic of Korea.

Protein science : a publication of the Protein Society
|January 20, 2026
PubMed
概括

研究人员发现了一种新的蛋白质分解途径,限制了TAT-融合蛋白质的核输送. 抑制calpain或MMP-3可以恢复核积累,改善治疗载体设计.

关键词:
脚部疼痛 脚部疼痛TAT 蛋白质转导域是一个 TAT 蛋白质转导域.基质金属蛋白酶-3的基因.核转移的转移是核转移的转移.蛋白质溶解裂变的发生.

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