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Updated: Jan 22, 2026

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人类急性和慢性免疫缺陷病毒中的线粒体DNA片段动力学:来自人类和非人类灵长类动物模型的见解

Jing Sun1, Lolita S Nidadavolu2, Hsing-Yu Hsu1

  • 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

The Journal of infectious diseases
|January 20, 2026
PubMed
概括

循环无细胞线粒体DNA (ccf-mtDNA) 水平在HIV-1 (PWH) 患者中较低,并且随着疾病的晚期而下降. 在SIV感染的NHP中,ART治疗也减少了ccf-mtDNA.

关键词:
艾滋病病毒-1 艾滋病病毒-1衰老的衰老 衰老的衰老没有细胞的DNA片段.纵向队列是一种纵向队列.非人类灵长类的灵长类.

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