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Updated: Jan 22, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
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A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

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通过AlphaFold,ESMFold和ProteinMPNNN评估单质蛋白质设计成功的零射击预测

Mario Garcia1, Sugyan M Dixit1, Gabriel J Rocklin1,2

  • 1Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Protein science : a publication of the Protein Society
|January 20, 2026
PubMed
概括

像AlphaFold和ESMFold这样的计算模型可以部分预测新型蛋白质设计的成功. 然而,它们的准确性是有限的,这凸显了对可靠的实验验证的任务特定培训的需要.

关键词:
一个新的蛋白质设计.蛋白质生物物理学的生物物理学序列预测 序列预测结构预测 结构预测

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