减少青少年的自我伤害:RISA-IPD综合摘要
David Cottrell1, Rebecca Walwyn2, Amanda Farrin2
1Division of Psychological & Social Medicine, Leeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, UK.
Health technology assessment (Winchester, England)
|January 20, 2026
概括
这次元分析没有发现任何证据表明,治疗干预可以减少青少年反复自我伤害. 然而,先前有多次自我伤害事件的参与者显示治疗效果有所改善,这表明潜在的亚组益处.
科学领域:
- 青少年心理健康研究研究
- 公共卫生干预措施 公共卫生干预措施
- 基于证据的实践实践.
背景情况:
- 自伤是青少年的重大公共卫生问题,缺乏有效干预措施的证据.
- 个人参与者数据的元分析为评估治疗效果和确定量身定制的治疗方法提供了强大的方法.
研究的目的:
- 系统地审查和进行随机对照试验 (RCT) 的个人参与者数据元分析,用于旨在减少青少年反复自我伤害的治疗干预.
- 探索各种干预措施的有效性,并确定哪些治疗方法最适合特定的青少年子组.
主要方法:
- 对涉及有史以来自伤青少年 (11-18岁) 的RCT进行了系统审查和个人参与者数据的元分析.
- 包括26项研究的个人参与者数据 (3448名参与者) 和7项额外研究的综合数据 (698名参与者).
- 两阶段的随机效应模型被用于分析初级 (在12个月内重复自我伤害) 和二次结果,而元回归则探索调节者.
主要成果:
- 没有发现有意义的证据表明,任何治疗干预措施,总体或特定类型,在12个月后预防重复自我伤害方面比对照更有效.
- 参与者之前有多次自我伤害事件,在6-12个月之间显著改善了治疗对自我伤害重复的效果.
- 温和的证据表明,基于参与者的年龄,性别,自我伤害方法和焦虑程度,治疗效果有所差异.
结论:
- 目前的治疗干预措施在减少青少年反复自我伤害方面没有显示出整体有效性.
- 未来的研究应该集中在适应性平台试验设计上,以有效地确定针对特定青少年子组最有效的干预措施.
- 改进的数据共享同意和标准化的结果报告对于未来在该领域的研究至关重要.
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