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Updated: Jan 22, 2026

Introducing Point Mutations into Human Pluripotent Stem Cells Using Seamless Genome Editing
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Introducing Point Mutations into Human Pluripotent Stem Cells Using Seamless Genome Editing

Published on: May 10, 2020

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艾滋病毒+扩散型大B细胞淋巴瘤的突变概况揭示了明显的突变特征,有基因组不稳定的证据

Sophia M Roush1, Samantha Beck1, Jenny Coelho1

  • 1Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina (UNC), Chapel Hill, NC, USA.

AIDS (London, England)
|January 20, 2026
PubMed
概括

艾滋病毒 (人类免疫缺陷病毒) 和扩散性大B细胞淋巴瘤 (DLBCL) 患者表现出明显的瘤突变. 之前的抗逆转录病毒治疗与较高的瘤突变负担和HIV+ DLBCL中的新抗原负载相关.

关键词:
非洲 非洲 非洲艾滋病病毒 艾滋病病毒 艾滋病病毒抗逆转录病毒药物治疗生物标志物 生物标志物扩散大的B细胞淋巴瘤.基因组学就是基因组学.微卫星的不稳定性新抗原是一种新抗原.

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